Using UHPLC-Triple Quadrupole MS/MS to Detect the Presence of Bark Extract and Yohimbine Adulteration in Dietary Supplements and Botanicals Authors
نویسنده
چکیده
A method using QuEChERS sample preparation and an Agilent 6490 Triple Quadrupole LC/MS has been developed that provides rapid and sub-parts per billion (ppb) detection of synthetic yohimbine and yohimbe bark extract in dietary supplements. Using the chromatographic separation of the diastereomers of yohimbine, the synthetic compound can be distinguished from the tree bark extract. An Agilent 6550 Q-TOF LC/MS system was used to confirm the presence of yohimbine and ajmalicine diastereomers, and the absence of any previously unidentified analogs.
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